"As the Spanish seized ever more land, Columbus implemented the repartimiento (or encomienda), which gave each of the conquerors a number of Indians to enslave, turning the natives’ previously peaceful way of life into a nightmare of unending brutality and violence as they were forced to mine precious metals and work plantations in sub-human conditions.
This subjugation was repeated throughout the Caribbean, before the conquistadores turned to the mainland, and wreaked the same carnage on the Aztecs of Mexico, the Maya of Central America, the Incas of Peru and Chile, and the other Indians they found."
"This same pattern of annihilation and conquest was repeated throughout Central and South America. Tens of millions of Indians were rounded up and used as slaves on the coca plantations, or as labour down the gold and silver mines, where they worked and slept without ever seeing the light of day, constantly exposed to highly toxic cinnabar, arsenic, and mercury. Life expectancy was brutally low.
The conquistadores calculated that with such an abundant slave workforce, it was cheaper to let them die of starvation and exhaustion than waste time and money providing food or survivable conditions. One conquistador recalled, “If twenty healthy Indians enter [a mine] on Monday, half may emerge crippled on Saturday”.
"In shockingly few generations, European greed, savagery, and disease had exterminated all but a handful of the citizens of the millennia-old American Indian civilisations. On average, the tribes’ populations were reduced to around 5 per cent of the size they had been before Columbus arrived."
Columbus, greed, slavery, and genocide: what really happened to the American Indians – Telegraph Blogs